
2012.09–2016.06 中國藥科大學 藥學(國家生命科學與技術人才培養(yǎng)基地班)本科
2016.09–2021.06?中國科學院上海有機化學研究所博士研究生(導師:卿鳳翎)
2021.10–2023.06 康奈爾大學和普林斯頓大學博士后(導師:Todd K. Hyster)
2023.06-2026.05?伊利諾伊大學厄巴納-香檳分校和霍華德·休斯醫(yī)學研究所 (導師:Wilfred?van der Donk)
2026.05–至今 ???中國科學院上海有機化學研究所 研究員
(1)生物催化;(2)生物工程:環(huán)肽展示和大環(huán)肽從頭發(fā)現;(3)天然產物生物合成
2021 中國科學院大學優(yōu)秀畢業(yè)生
2021 中國科學院大學院長優(yōu)秀獎
2020 中國科學院唐立新獎學金
2020 研究生國家獎學金
2019 中國科學院大學優(yōu)秀學生
1.?Ouyang, Y*#.; Nadeem,?H.#; Shukla, D.*; van der Donk, W. A*. In preparation
2.?Ouyang, Y.; Yu, Y.; Zhu, L.-Y.; Nguyen, D. T.; van der Donk, W. A*. Oxidative Peptide Backbone Cleavage by a HEXXH Enzyme During RiPP Biosynthesis. J. Am. Chem. Soc. 2026, 148, 3551.
3.?Ouyang, Y.#;?Wang, S.#; Sorigue,?D.;?Hyster, T. K*. Nucleophilic α-Functionalization of Benzyl Amines Using an Engineered Threonine Aldolase. J. Am. Chem. Soc. 2025, 147, 25184.
4.?Liu, S.; Zhou, J.; Yu, L.; Liu, Y.; Huang, Y.*; Ouyang, Y.*; Liu, G.-K.*; Xu, X.-H.*; Shibata, N*. Nitrogen-Based Organofluorine Functional Molecules: Synthesis and Applications. Chem. Rev.?2025, 125, 4603.?
5.?Ouyang, Y.#;?Page, C. G.?#; Bilodea, C.#; Hyster, T. K*. Synergistic Photoenzymatic Catalysis Enables Synthesis of α-Tertiary Amino Acids Using Threonine Aldolases.?J. Am. Chem. Soc. 2024, 146, 13754.
6.?Ouyang, Y.;?Qing, F.-L*. Photoredox Catalyzed Radical Fluoroalkylation with Non-Classical Fluorinated Reagents. J.?Org. Chem. 2024, 89, 2815.
7.?Ouyang, Y.; Turek-Herman, J.; Qiao, T.; Hyster, T. K*. Asymmetric Carbohydroxylation of Alkenes Using Photoenzymatic Catalysis. J. Am. Chem. Soc. 2023, 145, 17018.
8.?Emmanuel, M. A.; Bender, S. G.; Bilodeau, C.; Carceller, J. M.; DeHovitz, J. S.; Fu, H.; Liu, Y.; Nicholls, B. T.; Ouyang, Y.; Page, C. G.; Qiao, T.; Raps, F. C.; Sorigué, D. R.; Sun, S.; Turek-Herman, J.; Ye, Y.; Rivas-Souchet, A.; Cao, J.; Hyster, T. K*. Photobiocatalytic Strategies for Organic Synthesis. Chem. Rev.?2023, 123, 5459.
9.?Ouyang, Y.; Xu, X.-H.; Qing, F.-L*.?Electrochemical Trifluoromethoxylation of (Hetero)aromatics with a Trifluoromethyl Source and Oxygen. Angew. Chem. Int. Ed. 2022, 61, e202114048.
10.?Ouyang, Y.; T, C.-L.; Xu, X.-H.; Qing, F.-L*. Copper and Zinc Copromoted Bromo(Chloro)trifluoromethylation of Alkenes and Alkynes with Trifluoromethanesulfonic Anhydride. Org. Lett. 2021, 23, 346.
11.?Ouyang, Y.; Xu, X.-H.; Qing, F.-L*. Oxidative Coupling Reactions of Arylboronic Acids and Fluoroform-Derived AgCF3. Chin. J. Org.?Chem.?2020,?40, 3426.
12.?Ouyang, Y.; Xu, X.-H.; Qing, F.-L*. Hydrotrifluoromethylthiolation of Unactivated Alkenes and Alkynes with Trifluoromethanesulfonic Anhydride through Deoxygenative Reduction and Photoredox Radical Processes. Angew. Chem. Int. Ed.?2019,?58, 18508.
13.?Xiang, J.-X.; Ouyang, Y.; Xu, X.-H.; Qing, F.-L*.?Argentination of Fluoroform: Preparation of Stable AgCF3?Solution with Diverse Reactivities. Angew. Chem. Int. Ed.?2019,?58, 10320.?
14.?Ouyang, Y.; Xu, X.-H.; Qing, F.-L*. Trifluoromethanesulfonic Anhydride as a Low-cost and Versatile Trifluoromethylation Reagent.?Angew. Chem. Int. Ed. 2018, 57, 6926.
15.?Yu, W.; Ouyang,?Y.; Xu, X.-H.; Qing, F.-L*. Visible Light-Induced Methoxycarbonyldifluoromethylation of Trimethylsilyl Enol Ethers and Allyltrimethylsilanes with FSO2CF2CO2Me. Chin. J. Chem.?2018,?36,?1024.
Book Chapter:
Ouyang, Y.; Shou, J.-Y.; Qing, F.-L*.?Science of Synthesis: Base-Metal Catalysis, Yoshikai, N., Ed.; Thieme: Stuttgart (2022); Vol. 1, p245-324. DOI: 10.1055/sos-SD-238-00130.
(# Contributed equally, *Corresponding author)

