
教育經(jīng)歷:
2006-2010? 吉林大學(xué)?學(xué)士學(xué)位
2010-2015?清華大學(xué)?博士學(xué)位
工作經(jīng)歷
2016-2021? OHSU/HHMI 博士后
2021.12 -至今中國科學(xué)院有機(jī)化學(xué)研究所 研究員、課題組組長
1.?Yu J*, Rao P*, Clark S, Mitra J, Ha T and Gouaux E. Hippocampal AMPA receptor assemblies and mechanism of allosteric inhibition (2021).?Nature, 594(7863):448-453.?
2.?Yu J*, Zhu H*, Lape R, Greiner T, Du J, Lü W, Sivilotti L, Gouaux E. Mechanism of gating and partial agonist action in the glycine receptor (2021).?Cell, 184:957-968.e21.?
3. Phulera S*, Zhu H*,?Yu J*, Claxton DP, Yoder N, Craig Yoshioka C, Gouaux E. Cryo-EM structure of the benzodiazepine-sensitive α1β1γ2S tri-heteromeric GABAA receptor in complex with GABA (2018).?eLife, 7:e39383.
4.?Yu J.*, Zhang B, Zhang Y, Xu CQ, Zhuo W, Ge J, Li J, Gao N, Li Y, Yang M. A binding-block ion selective mechanism revealed by a Na/K selective channel (2018).?Protein Cell, 9(7):629-639.?
5.?Yu J*, Ge J*., Heuveling J, Schneider E, and Yang M. Structural basis for substrate specificity of an amino acid ABC transporter (2015).?Proc Natl Acad Sci USA, 112, 5243-5248.?
6.?Yu J*, Pian Y*, Ge J*, Guo J, Zheng Y, Jiang H, Hao H, Yuan Y, Jiang Y, and Yang M.? Functional and structural characterization of the antiphagocytic properties of a novel transglutaminase from streptococcus suis (2015).?J. Bio. Chem, 290, 19081-19092.?
7. Ivica J, Lape R, Jazbec V,?Yu J, Zhu H, Gouaux E, Sivilotti LG. The intracellular domain of homomeric glycine receptors modulates agonist efficacy (2021).??J. Bio. Chem, 296, 100387.
8. Yang Y, Yu Y, Li X, Li J, Wu Y,?Yu J, Ge J, Huang Z, Jiang L, Rao Y, Yang M. Target elucidation by cocrystal structures of NADH-Ubiquinone oxidoreductase of Plasmodium falciparum (PfNDH2) with small molecule to eliminate drug-resistant malaria (2017).??J. Med. Chem, 60(5):1994-2005.?
9. Zhang X, Wang J, Feng Y, Ge J, Li W, Sun W, Iscla I,?Yu J, Blount P, Li Y, Yang M. Structure and molecular mechanism of an anion-selective mechanosensitive channel of small conductance (2012).?Proc Natl Acad Sci USA, 109, 18180-18185.

