2018年10月26日,『生命有機(jī)化學(xué)國家重點(diǎn)實(shí)驗(yàn)室』和『手性科學(xué)伙伴國家重點(diǎn)實(shí)驗(yàn)室』在香港理工大學(xué)舉行了伙伴實(shí)驗(yàn)室年度學(xué)術(shù)交流會(huì)議。黃國賢教授首先介紹了伙伴實(shí)驗(yàn)室正式通過科技部的驗(yàn)收,并更名為『化學(xué)生物學(xué)及藥物研發(fā)國家重點(diǎn)實(shí)驗(yàn)室 The State Key Laboratory of Chemical Biology and Drug Discovery』,在研究方向、硬件和人才布局等方面都有了進(jìn)一步的發(fā)展。21位研究人員分別就各自課題的最新研究進(jìn)展做了學(xué)術(shù)報(bào)告,并對(duì)其中展現(xiàn)的熱點(diǎn)科學(xué)問題和技術(shù)手段進(jìn)行了熱烈討論。同時(shí),經(jīng)過八年的不斷交流,合作課題也越來越廣泛和深入。
學(xué)術(shù)報(bào)告如下:
- (1)馬大為 研究員:Total Synthesis of Bioactive Alkaloids
- (2)梁潤松 教授:Human Arginase Drug Development: an Update
- (3)俞飚 研究員:Chemical Synthesis of Biologically Significant Marine Saponins
- (4)趙燕湘 教授:Structural Study of the Mammalian Beclin2 to Delineate its Distinct Roles in Regulating Autophagy and GPCR Trafficking
- (5)唐功利 研究員:Biosynthesis of High-active Alkaloids Bicyclomycin and CC-1065
- (6)周銘祥 教授:Design of Specific Notch1 Inhibitors
- (7)陳以昀 研究員:Visible-Light-Induced Bond-Forming and Bond-Cleavage Reactions and Their Biological Applications
- (8)陳聲 教授:Research Updates on mcr-1, a Plasmid Mediated Colistin Resistance Gene
- (9)周佳海 研究員:Discovery of a Natural-product Herbicide With a New Mode of Action
- (10)黃文健 博士:Gold Catalysis and Silver-mediated Bioconjugation
- (11)曹春陽 研究員:Antiepilepsy effects of small peptide targeting BK channels (a+beta4) subtype
- (12)李建華 博士:EPH receptor B2 augments cancer stemness and drug resistance via a Wnt positive signaling loop in hepatocellular carcinoma
- (13)余永耀 教授:Enantioselective Ruthenium-Catalyzed Intramolecular Amidation of C(sp3)-H Bond to Form γ-Lactams
- (14)潘李鋒 研究員:Structural Characterizations of the Autophagy Receptor NDP52 and TAX1BP1
- (15)姚鍾平 博士:Chiral Recognition by Mass Spectrometry
- (16)康經(jīng)武 研究員:Micro Column Affinity Chromatography for Drug Target Identification
- (17)柯子斌 博士:CTCF in Liver Cancer and Drug Discovery of Novel CTCF inhibitors
- (18)王婧 研究員:Mechanism Based MITF Inhibition by Selective Small Molecular for Melanoma Treatment
- (19)趙倩 博士:Chemical Proteomics Approaches for Drug Target Identification and Beyond
- (20)房鵬飛 研究員:Adaptation to Non-canonical Function by Dynamic Adjustment in Lysyl-tRNA Synthetases
- (21)馬聰 博士:Targeting Protein-Protein Interactions for Antimicrobial Discovery

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